Short Tandem Repeat profiling, or STR profiling, is a fast, repeatable and standardized PCR-based method for the certain identification or authentication of human cell lines with resolution down to the individual donor. And as misidentified cell lines continue to plague research, authentication of human cell lines via STR profile analysis is becoming a requirement of many journals and funding agencies.
Many continuous cell lines — especially cancer cell lines — are karyotypically abnormal or genetically unstable, making data interpretation difficult. Take advantage of our decades of experience with STR profiling and our unmatched expertise in interpreting data from over a thousand cancer cell lines. Send your human cell lines to the atcc cell line authentication Testing Service for STR profile analysis.
The validity of research data relies heavily on the identity of the cell line used in testing. According to the American Type Culture Collection Standards Development Organization Workgroup (SDO), only 33% of researchers test the authenticity of their cell lines. To highlight the problem, the National Institutes of Health (NIH), which states that “misidentification of cell cultures is a serious problem.”
In addition, standards approved by the American National Standards Institute (ANSI), were issued in 2012 by the ATCC SDO Workgroup to promote authentication of cell lines utilizing STR DNA technology.
Cell line authentication puts your mind at ease about all of the hard work and time you have put into your research.